Sunday 5 August 2018


Malignant mesothelioma (MM)  is a highly invasive tumor  arising from the mesothelial cells of serosal surfaces. It shows an extremely poor  progression and is diagnosed mostly in locally advanced  or metastatic stage, thus  drastically limiting its  treatment options. Past asbestos  exposure has been shown to  be the most important predictor of MM, although other  environmental and genetic  factors like Simian Virus-40 (SV-40) infection and genetic  predisposition might also  play important roles.

This book brings together  the knowledge of experts in  the filed of malignant mesothelioma who provide  their invaluable insights  into this deadly disease  from different perspectives.

Chapter 1 Mineralogy and  Malignant Mesothelioma: The South African  Experience 1
Chapter 2 Effect of Asbestos on Anti-Tumor  Immunity and Immunological Alteration in Patients with Malignant Mesothelioma
Chapter 3 Role of  Inflammation and Angiogenic Growth Factors in Malignant Mesothelioma
Chapter 4 The Role of  Cyclooxygenase-2, Epidermal  Growth Factor Receptor and Aromatase in  Malignant Mesothelioma
Chapter 5 Neoadjuvant  Chemotherapy in Malignant Pleural  Mesothelioma

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